Towards a dynamic covalent molecular switch: substituent effects in chalcone/flavanone isomerism.

نویسندگان

  • Jesse Mai
  • Ermal Hoxha
  • Caitlin E Morton
  • Brian M Muller
  • Marc J Adler
چکیده

Chalcone/flavanone interconversion occurs facilely under aqueous alkaline conditions making it a promising scaffold for the development of a covalent molecular switch. In this study, a single methoxy substituent is shown to have a significant impact on the equilibrium dynamics of this reaction; this impact is dependent on the site of substitution.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 11 21  شماره 

صفحات  -

تاریخ انتشار 2013